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Central diabetes insipidus, recently renamed arginine vasopressin deficiency (AVP-D), [ 1] is a form of diabetes insipidus that is due to a lack of vasopressin (ADH) production in the brain. Vasopressin acts to increase the volume of blood (intravascularly), and decrease the volume of urine produced. Therefore, a lack of it causes increased ...
Diabetes insipidus. Diabetes insipidus ( DI) (arginine vasopressin disorder), alternately called arginine vasopressin deficiency (AVP-D) or arginine vasopressin resistance (AVP-R), [ 5] is a condition characterized by large amounts of dilute urine and increased thirst. [ 1] The amount of urine produced can be nearly 20 liters per day. [ 1]
Fluid deprivation test. A fluid or water deprivation test is a medical test [ 1] which can be used to determine whether the patient has diabetes insipidus as opposed to other causes of polydipsia (a condition of excessive thirst that causes an excessive intake of water). The patient is required, for a prolonged period, to forgo intake of water ...
Desmopressin. Desmopressin, sold under the trade name DDAVP among others, is a medication used to treat diabetes insipidus, bedwetting, hemophilia A, von Willebrand disease, and high blood urea levels. [ 1] In hemophilia A and von Willebrand disease, it should only be used for mild to moderate cases. [ 1]
Polyuria, nocturia, and polydipsia. Nephrogenic diabetes insipidus, recently renamed arginine vasopressin resistance (AVP-R) and previously known as renal diabetes insipidus, is a form of diabetes insipidus primarily due to pathology of the kidney. This is in contrast to central or neurogenic diabetes insipidus, which is caused by insufficient ...
Vasopressin is used to manage anti-diuretic hormone deficiency. Vasopressin is used to treat diabetes insipidus related to low levels of antidiuretic hormone. It is available as Pressyn. [53] Vasopressin has off-label uses and is used in the treatment of vasodilatory shock, gastrointestinal bleeding, ventricular tachycardia and ventricular ...
Wolfram syndrome, also called DIDMOAD ( d iabetes i nsipidus, d iabetes m ellitus, o ptic a trophy, and d eafness), is a rare autosomal-recessive genetic disorder that causes childhood-onset diabetes mellitus, optic atrophy, and deafness as well as various other possible disorders including neurodegeneration.
Chlortalidone (or other thiazide medication) is a key component of treatment of nephrogenic diabetes insipidus. Nephrogenic diabetes insipidus occurs when the kidney is unable to concentrate urine because it has an inadequate response to vasopressin-dependent removal of free water from the renal tubular filtrate.