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Oclacitinib. Oclacitinib, sold under the brand name Apoquel among others, is a veterinary medication used in the control of atopic dermatitis and pruritus from allergic dermatitis in dogs at least 12 months of age. [ 1 ][ 4 ] Chemically, it is a synthetic cyclohexylamino pyrrolopyrimidine janus kinase inhibitor that is relatively selective for ...
A Janus kinase inhibitor, also known as JAK inhibitor or jakinib, [1] is a type of immune modulating medication, which inhibits the activity of one or more of the Janus kinase family of enzymes (JAK1, JAK2, JAK3, TYK2), thereby interfering with the JAK-STAT signaling pathway in lymphocytes. JAK inhibitors are used in the treatment of some ...
Apoquel is a medication prescribed for pets — particularly dogs — to alleviate symptoms associated with allergic dermatitis, such as itching and inflammation. The FDA has not officially ...
Muscarinic acetylcholine receptor antagonist. This means quetiapine is a dopamine, serotonin, and adrenergic antagonist, and a potent antihistamine with some anticholinergic properties. [76] Quetiapine binds strongly to serotonin receptors; the drug acts as partial agonist at 5-HT 1A receptors. [77]
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Identifiers. CAS Number. 1533403-95-0 Y. UNII. 3D6091GOHH. Lokivetmab, trade name Cytopoint, is a monoclonal antibody used to treat atopic dermatitis in dogs. [1] It acts against interleukin 31 (IL-31), [2] which is a cytokine involved in causing itchiness (pruritus). [2] Lokivetmab is administered by subcutaneous injection; each dose is ...
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