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Original logo (used until 1993, but carried by stores until 1997) Costco Wholesale Corporation is an American multinational corporation which operates a chain of membership-only big-box warehouse club retail stores. [4] As of 2021, Costco is the third-largest retailer in the world [5] and is the world's largest retailer of choice and prime beef ...
The metabolic half-life is 8 to 59 hours (approximately 24 hours for opioid-tolerant people, and 55 hours in opioid-naive people), as opposed to a half-life of 1 to 5 hours for morphine. [12] The length of the half-life of methadone allows for exhibition of respiratory depressant effects for an extended duration of time in opioid-naive people.
80,000 Hours' primary focus is on advising talented graduates between the ages of 20 and 40. [ 10 ] It advocates longtermism , the view that improving the long-term future is a moral priority, due to the large number of people who will or could exist in the future.
Coupons are normally described in terms of the "coupon rate", which is calculated by adding the sum of coupons paid per year and dividing it by the bond's face value. [2] For example, if a bond has a face value of $1,000 and a coupon rate of 5%, then it pays total coupons of $50 per year.
Death Valley, a desert with large expanses below sea level, is considered the hottest location in the world; the highest temperature in the world, [135] [136] 134 °F (56.7 °C), was recorded there on July 10, 1913. The lowest temperature in California was −45 °F (−43 °C) on January 20, 1937, in Boca. [137]
To put in perspective the size of a googol, the mass of an electron, just under 10 −30 kg, can be compared to the mass of the visible universe, estimated at between 10 50 and 10 60 kg. [5] It is a ratio in the order of about 10 80 to 10 90 , or at most one ten-billionth of a googol (0.00000001% of a googol).
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