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Mast cell activation was assigned an ICD-10 code (D89.40, along with subtype codes D89.41-43 and D89.49) in October 2016. [18] According to the American Academy of Allergy, Asthma, and Immunology (AAAI), the most precise method of diagnosing MCAS is through a bone marrow biopsy and aspirate. [16]
Acute severe asthma. Silent chest, worsening symptoms despite use of medication. [1] Acute severe asthma, also known as status asthmaticus, is an acute exacerbation of asthma that does not respond to standard treatments of bronchodilators (inhalers) and corticosteroids. [2] Asthma is caused by multiple genes, some having protective effect, with ...
Paroxysmal nocturnal dyspnea or paroxysmal nocturnal dyspnoea ( PND) is an attack of severe shortness of breath and coughing that generally occurs at night. [ 1] It usually awakens the person from sleep, and may be quite frightening. [ 2] PND, as well as simple orthopnea, may be relieved by sitting upright at the side of the bed with legs ...
AERD affects an estimated 0.3–0.9% of the general population in the US, including around 7% of all asthmatics, about 14% of adults with severe asthma, and ~5-10% of patients with adult onset asthma. [2] [3] [8] AERD is uncommon among children, with around 6% of patients, predominantly female, reporting disease onset during childhood. [9]
Specialty. Pulmonology. Bronchospasm or a bronchial spasm is a sudden constriction of the muscles in the walls of the bronchioles. It is caused by the release ( degranulation) of substances from mast cells or basophils under the influence of anaphylatoxins. It causes difficulty in breathing which ranges from mild to severe.
Reactive airway disease. Reactive airway disease ( RAD) is an informal label that physicians apply to patients with symptoms similar to those of asthma. [ 1] An exact definition of the condition does not exist. [ 1][ 2] Individuals who are typically labeled as having RAD generally have a history of wheezing, coughing, dyspnea, and production of ...
Cardiac asthma is the medical condition of intermittent wheezing, coughing, and shortness of breath that is associated with underlying congestive heart failure (CHF). [ 1] Symptoms of cardiac asthma are related to the heart's inability to effectively and efficiently pump blood in a CHF patient. [ 2] This can lead to accumulation of fluid in and ...
Bronchial hyperresponsiveness (or other combinations with airway or hyperreactivity, BH used as a general abbreviation) [1] is a state characterised by easily triggered bronchospasm (contraction of the bronchioles or small airways). Bronchial hyperresponsiveness can be assessed with a bronchial challenge test. This most often uses products like ...