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Kleiber's plot comparing body size to metabolic rate for a variety of species. [1] Kleiber's law, named after Max Kleiber for his biology work in the early 1930s, is the observation that, for the vast majority of animals, an animal's metabolic rate scales to the 3⁄4 power of the animal's mass. [2] More recently, Kleiber's law has also been ...
Allele frequency. Allele frequency, or gene frequency, is the relative frequency of an allele (variant of a gene) at a particular locus in a population, expressed as a fraction or percentage. [1] Specifically, it is the fraction of all chromosomes in the population that carry that allele over the total population or sample size.
Allele. An allele[ 1], or allelomorph, is a variant of the sequence of nucleotides at a particular location, or locus, on a DNA molecule. [ 2] Alleles can differ at a single position through single nucleotide polymorphisms (SNP), [ 3] but they can also have insertions and deletions of up to several thousand base pairs. [ 4]
Repeated sequences (also known as repetitive elements, repeating units or repeats) are short or long patterns that occur in multiple copies throughout the genome. In many organisms, a significant fraction of the genomic DNA is repetitive, with over two-thirds of the sequence consisting of repetitive elements in humans. [ 1]
Bacterial conjugation is the transfer of genetic material between bacterial cells by direct cell-to-cell contact or by a bridge-like connection between two cells. [ 1] This takes place through a pilus. [ 2][full citation needed] It is a parasexual mode of reproduction in bacteria. A micrograph displaying Escherichia coli undergoing bacterial ...
Fold change. Fold change is a measure describing how much a quantity changes between an original and a subsequent measurement. It is defined as the ratio between the two quantities; for quantities A and B the fold change of B with respect to A is B / A. In other words, a change from 30 to 60 is defined as a fold-change of 2.
The absolute bioavailability is the dose-corrected area under curve ( AUC) non-intravenous divided by AUC intravenous. The formula for calculating the absolute bioavailability, F, of a drug administered orally (po) is given below (where D is dose administered). Therefore, a drug given by the intravenous route will have an absolute ...
The surface-area-to-volume ratio has physical dimension inverse length (L −1) and is therefore expressed in units of inverse metre (m -1) or its prefixed unit multiples and submultiples. As an example, a cube with sides of length 1 cm will have a surface area of 6 cm 2 and a volume of 1 cm 3. The surface to volume ratio for this cube is thus.