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Analgesic nephropathy is injury to the kidneys caused by analgesic medications such as aspirin, bucetin, phenacetin, and paracetamol. The term usually refers to damage induced by excessive use of combinations of these medications, especially combinations that include phenacetin. It may also be used to describe kidney injury from any single ...
Frequency. >100,000 per year (US) [ 1] Paracetamol poisoning, also known as acetaminophen poisoning, is caused by excessive use of the medication paracetamol (acetaminophen). [ 2] Most people have few or non-specific symptoms in the first 24 hours following overdose. These symptoms include feeling tired, abdominal pain, or nausea.
Nonsteroidal anti-inflammatory drug. Non-steroidal anti-inflammatory drugs[ 1][ 3] ( NSAID) [ 1] are members of a therapeutic drug class which reduces pain, [ 4] decreases inflammation, decreases fever, [ 1] and prevents blood clots. Side effects depend on the specific drug, its dose and duration of use, but largely include an increased risk of ...
Paracetamol. Paracetamol ( acetaminophen[ a]) is a non-opioid analgesic and antipyretic agent used to treat fever and mild to moderate pain. [ 13][ 14][ 15] It is a widely used over the counter medication. Common brand names include Tylenol and Panadol .
Nephrotoxicity. Nephrotoxicity is toxicity in the kidneys. It is a poisonous effect of some substances, both toxic chemicals and medications, on kidney function. [ 1] There are various forms, [ 2] and some drugs may affect kidney function in more than one way. Nephrotoxins are substances displaying nephrotoxicity.
In terms of cause, almost any condition that involves ischemia can lead to renal papillary necrosis. A mnemonic for the causes of renal papillary necrosis is POSTCARDS: pyelonephritis, obstruction of the urogenital tract, sickle cell disease, tuberculosis, cirrhosis of the liver, analgesia/alcohol use disorder, renal vein thrombosis, diabetes mellitus, and systemic vasculitis. [3]
Acute liver failure is the appearance of severe complications rapidly after the first signs (such as jaundice) of liver disease, and indicates that the liver has sustained severe damage (loss of function of 80–90% of liver cells). The complications are hepatic encephalopathy and impaired protein synthesis (as measured by the levels of serum ...
Anti-inflammatory or antiphlogistic is the property of a substance or treatment that reduces inflammation or swelling. Anti-inflammatory drugs, also called anti-inflammatories, make up about half of analgesics. These drugs remedy pain by reducing inflammation as opposed to opioids, which affect the central nervous system to block pain signaling ...