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Myxedema coma is an extreme or decompensated form of hypothyroidism and while uncommon, is potentially lethal. [ 1][ 2][ 3] A person may have laboratory values identical to a "normal" hypothyroid state, but a stressful event (such as an infection, myocardial infarction, or stroke) precipitates the myxedema coma state, usually in the elderly.
The primary treatment of thyroid storm is with inorganic iodine and antithyroid drugs (propylthiouracil or methimazole) to reduce synthesis and release of thyroid hormone. Temperature control and intravenous fluids are also mainstays of management. Beta blockers are often used to reduce the effects of thyroid hormone. [5]
Propylthiouracil is in the antithyroid family of medications. [4] It works by decreasing the amount of thyroid hormone produced by the thyroid gland and blocking the conversion of thyroxine (T4) to triiodothyronine (T3). [3] Propylthiouracil came into medical use in the 1940s. [5] It is on the World Health Organization's List of Essential ...
Wilson's ( temperature) syndrome, also called Wilson's thyroid syndrome or WTS, is a term used in alternative medicine to improperly attribute various common and non-specific symptoms to abnormally low body temperature and impaired conversion of thyroxine (T4) to triiodothyronine (T3), despite normal thyroid function tests. [ 1] E.
Levothyroxine. Levothyroxine, also known as L-thyroxine, is a synthetic form of the thyroid hormone thyroxine (T 4 ). [ 5][ 8] It is used to treat thyroid hormone deficiency (hypothyroidism), including a severe form known as myxedema coma. [ 5] It may also be used to treat and prevent certain types of thyroid tumors. [ 5]
Antihypertensive. Antihypertensives are a class of drugs that are used to treat hypertension (high blood pressure). [ 1] Antihypertensive therapy seeks to prevent the complications of high blood pressure, such as stroke, heart failure, kidney failure and myocardial infarction. Evidence suggests that reduction of the blood pressure by 5 mmHg can ...
Blood pressure varies over longer time periods (months to years) and this variability predicts adverse outcomes. [20] Blood pressure also changes in response to temperature, noise, emotional stress, consumption of food or liquid, dietary factors, physical activity, changes in posture (such as standing-up), drugs, and disease. [21]
At the cellular level, T 3 is the body's more active and potent thyroid hormone. [2] T 3 helps deliver oxygen and energy to all of the body's cells, its effects on target tissues being roughly four times more potent than those of T 4. [2] Of the thyroid hormone that is produced, just about 20% is T 3, whereas 80% is produced as T 4.