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Triiodothyronine, also known as T3, is a thyroid hormone. It affects almost every physiological process in the body, including growth and development, metabolism, body temperature, and heart rate. [1]
The major form of thyroid hormone in the blood is thyroxine (T 4), whose half-life of around one week is longer than that of T 3. In humans, the ratio of T 4 to T 3 released into the blood is approximately 14:1. T 4 is converted to the active T 3 (three to four times more potent than T 4) within cells by deiodinases (5′-deiodinase).
Thyroid function tests ( TFTs) is a collective term for blood tests used to check the function of the thyroid. [1] TFTs may be requested if a patient is thought to suffer from hyperthyroidism (overactive thyroid) or hypothyroidism (underactive thyroid), or to monitor the effectiveness of either thyroid-suppression or hormone replacement therapy ...
Euthyroid sick syndrome. Euthyroid sick syndrome ( ESS) is a state of adaptation or dysregulation of thyrotropic feedback control [1] wherein the levels of T3 and/or T4 are abnormal, but the thyroid gland does not appear to be dysfunctional. This condition may result from allostatic responses of hypothalamus-pituitary-thyroid feedback control ...
Reverse triiodothyronine (3,3′,5′-triiodothyronine, reverse T 3, or rT 3) is an isomer of triiodothyronine (3,5,3′ triiodothyronine, T 3 ). Reverse T 3 is the third-most common iodothyronine the thyroid gland releases into the bloodstream, at 0.9%; tetraiodothyronine (levothyroxine, T 4) constitutes 90% and T 3 is 9%.
The hypothalamic–pituitary–thyroid axis ( HPT axis for short, a.k.a. thyroid homeostasis or thyrotropic feedback control) is part of the neuroendocrine system responsible for the regulation of metabolism and also responds to stress. As its name suggests, it depends upon the hypothalamus, the pituitary gland, and the thyroid gland .
Regarding ideal numbers, the famous M.D. says: "Your blood pressure is supposed to be under 140 over 90, optimally closer to 120 over 80." He went on to call the test "life-saving" and "the single ...
Thyroid hormone binding ratio (THBR) is a thyroid function test that measures the "uptake" of T3 or T4 tracer by thyroid-binding globulin (TBG) in a given serum sample. This provides an indirect and reciprocal estimate of the available binding sites on TBG within the sample. The results are then reported as a ratio to normal serum.