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The mainstay of type 1 diabetes treatment is the regular injection of insulin to manage hyperglycemia. [39] Injections of insulin via subcutaneous injection using either a syringe or an insulin pump are necessary multiple times per day, adjusting dosages to account for food intake, blood glucose levels and physical activity. [39]
Type 2 diabetes is generally treated with medication that is taken by mouth (e.g. metformin) although some eventually require injectable treatment with insulin or GLP-1 agonists. [122] Metformin is generally recommended as a first-line treatment for type 2 diabetes, as there is good evidence that it decreases mortality. [7]
[1] [3] It is estimated that type 1 diabetics experience two mild, symptomatic episodes of hypoglycemia per week. [3] Additionally, people with type 1 diabetes have at least one severe hypoglyemic episode per year, requiring treatment assistance. [3] In terms of mortality, hypoglycemia causes death in 6–10% of type 1 diabetics. [3 ...
Type 2 diabetes makes up about 90% of cases of diabetes, with the other 10% due primarily to type 1 diabetes and gestational diabetes. [1] In type 1 diabetes , there is a lower total level of insulin to control blood glucose, due to an autoimmune induced loss of insulin-producing beta cells in the pancreas .
Diabetic retinopathy (also known as diabetic eye disease ), is a medical condition in which damage occurs to the retina due to diabetes. It is a leading cause of blindness in developed countries. Diabetic retinopathy affects up to 80 percent of those who have had both type 1 and type 2 diabetes for 20 years or more.
Demonstration that intensive glycemic control in type 1 diabetes reduces chronic side effects more as glucose levels approach 'normal' in a large longitudinal study, [149] and also in type 2 diabetics in other large studies; Identification of the first thiazolidinedione as an effective insulin sensitizer during the 1990s
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