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Dengue fever is a mosquito-borne disease caused by dengue virus, prevalent in tropical and subtropical areas. It is frequently asymptomatic; if symptoms appear they typically begin 3 to 14 days after infection. These may include a high fever, headache, vomiting, muscle and joint pains, and a characteristic skin itching and skin rash.
Dengue virus ( DENV) is the cause of dengue fever. It is a mosquito -borne, single positive-stranded RNA virus of the family Flaviviridae; genus Flavivirus. [ 1][ 2] Four serotypes of the virus have been found, and a reported fifth has yet to be confirmed, [ 3][ 4][ 5] all of which can cause the full spectrum of disease. [ 1]
Crystal structure of the dengue virus, which causes dengue fever. ICD-10-PCS. A90. LOINC. 75377-2. NS1 antigen test (nonstructural protein 1) is a test for dengue, introduced in 2006. It allows rapid detection on the first day of fever, before antibodies appear some 5 or more days later. [ 1] It has been adopted for use in some 40 nations.
For perspective, there have been 2,559 cases of dengue fever reported in U.S. states and territories since the start of 2024, per the CDC. A large majority of those (1,724) were reported in Puerto ...
Causes. Dengue is a Flaviviridae virus, with five genetic types. [8] [9] Here is the virus drawn as a 3-dimensional model of the envelope protein. [10] Dengue is in the same family as other well known viruses carried by mosquitoes that cause tropical diseases, such as yellow fever, West Nile, and Zika virus. [11]
This year, the incidence of dengue fever globally has been the highest on record, especially in Latin American countries, where more than 9.7 million dengue cases have been reported. That's twice ...
Dengue vaccine is a vaccine used to prevent dengue fever in humans. [ 9] Development of dengue vaccines began in the 1920s, but was hindered by the need to create immunity against all four dengue serotypes. [ 10] As of 2023, there are two commercially available vaccines, sold under the brand names Dengvaxia and Qdenga. [ 11][ 12]
A positive tourniquet test on the right side of a patient with dengue fever. Note the increased number of petechia. A tourniquet test (also known as a Rumpel-Leede capillary-fragility test or simply a capillary fragility test) determines capillary fragility. It is a clinical diagnostic method to determine a patient's haemorrhagic tendency.