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An acid–base titration is a method of quantitative analysis for determining the concentration of Brønsted-Lowry acid or base (titrate) by neutralizing it using a solution of known concentration (titrant). [ 1] A pH indicator is used to monitor the progress of the acid–base reaction and a titration curve can be constructed.
The Henderson–Hasselbalch equation can be used to estimate the pH of a buffer solution by approximating the actual concentration ratio as the ratio of the analytical concentrations of the acid and of a salt, MA. The equation can also be applied to bases by specifying the protonated form of the base as the acid. For example, with an amine,
Titration. A burette and Erlenmeyer flask (conical flask) being used for an acid–base titration. Titration (also known as titrimetry[ 1] and volumetric analysis) is a common laboratory method of quantitative chemical analysis to determine the concentration of an identified analyte (a substance to be analyzed).
In Figure 1, the effect is illustrated by the simulated titration of a weak acid with pK a = 4.7. The relative concentration of undissociated acid is shown in blue, and of its conjugate base in red. The pH changes relatively slowly in the buffer region, pH = pK a ± 1, centered at pH = 4.7, where [HA] = [A −]. The hydrogen ion concentration ...
From Wikipedia, the free encyclopedia. In computational biology, protein pKacalculationsare used to estimate the pKavaluesof amino acidsas they exist within proteins. These calculations complement the pKavalues reported for amino acids in their free state, and are used frequently within the fields of molecular modeling, structural ...
A typical titration curve of a diprotic acid, oxalic acid, titrated with a strong base, sodium hydroxide.Both equivalence points are visible. Titrations are often recorded on graphs called titration curves, which generally contain the volume of the titrant as the independent variable and the pH of the solution as the dependent variable (because it changes depending on the composition of the ...
Equivalence point. The equivalence point, or stoichiometric point, of a chemical reaction is the point at which chemically equivalent quantities of reactants have been mixed. For an acid-base reaction the equivalence point is where the moles of acid and the moles of base would neutralize each other according to the chemical reaction.
A pH indicator is a halochromic chemical compound added in small amounts to a solution so the pH ( acidity or basicity) of the solution can be determined visually or spectroscopically by changes in absorption and/or emission properties. [ 1] Hence, a pH indicator is a chemical detector for hydronium ions (H 3 O +) or hydrogen ions (H +) in the ...