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Ewing sarcoma is a small-blue-round-cell tumor that typically has a clear cytoplasm on H&E staining, due to glycogen. The presence of the glycogen can be demonstrated with positive PAS staining and negative PAS diastase staining. The characteristic immunostain is CD99, which diffusely marks the cell membrane.
The International Classification of Diseases for Oncology (ICD-O) is a domain-specific extension of the International Statistical Classification of Diseases and Related Health Problems for tumor diseases. This classification is widely used by cancer registries. It is currently in its third revision (ICD-O-3). ICD-10 includes a list of ...
HeLa ( / ˈhiːlɑː /) is an immortalized cell line used in scientific research. It is the oldest human cell line and one of the most commonly used. [ 1][ 2] HeLa cells are durable and prolific, allowing for extensive applications in scientific study. [ 3][ 4] The line is derived from cervical cancer cells taken on February 8, 1951, [ 5] from ...
Combined small cell lung carcinoma (or c-SCLC) is a form of multiphasic lung cancer that is diagnosed by a pathologist when a malignant tumor, arising from transformed cells originating in lung tissue, contains a component of;small cell lung carcinoma (SCLC), admixed with one (or more) components of any histological variant of non-small cell lung carcinoma (NSCLC) in any relative proportion.
NCI/ADR-RES appears to have been derived at some point in time from cell line OVCAR-8. Originally the cell line was named MCF-7/ADR-RES; it was renamed together with the change in classification. Two brain cancer cell lines, SNB-19 and U251, were discovered to come from the same person. This makes a mixup likely.
FOXP3 ( forkhead box P3), also known as scurfin, is a protein involved in immune system responses. [ 5] A member of the FOX protein family, FOXP3 appears to function as a master regulator of the regulatory pathway in the development and function of regulatory T cells. [ 6][ 7][ 8] Regulatory T cells generally turn the immune response down.
The WHO model list of essential in vitro diagnostics, or WHO list of essential diagnostic tests (EDL) is a World Health Organization (WHO) priority list of medical tests that provides guidance for individual countries on which tests to use and which not to. [1] [2] It was first published in 2018, [1] [3] then revised in 2019, [1] [3] and a ...
Hard lump with a scaly top or ulceration. [ 1] Cutaneous squamous-cell carcinoma ( cSCC ), also known as squamous-cell carcinoma of the skin or squamous-cell skin cancer, is one of the three principal types of skin cancer, alongside basal-cell carcinoma and melanoma. [ 10] cSCC typically presents as a hard lump with a scaly surface, though it ...