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The WHO model list of essential in vitro diagnostics, or WHO list of essential diagnostic tests (EDL) is a World Health Organization (WHO) priority list of medical tests that provides guidance for individual countries on which tests to use and which not to. [1] [2] It was first published in 2018, [1] [3] then revised in 2019, [1] [3] and a ...
Patient derived xenograft. Patient derived xenografts ( PDX) are models of cancer where the tissue or cells from a patient's tumor are implanted into an immunodeficient or humanized mouse. [ 1] It is a form of xenotransplantation. PDX models are used to create an environment that allows for the continued growth of cancer after its removal from ...
NCI/ADR-RES appears to have been derived at some point in time from cell line OVCAR-8. Originally the cell line was named MCF-7/ADR-RES; it was renamed together with the change in classification. Two brain cancer cell lines, SNB-19 and U251, were discovered to come from the same person. This makes a mixup likely.
The International Classification of Diseases for Oncology (ICD-O) is a domain-specific extension of the International Statistical Classification of Diseases and Related Health Problems for tumor diseases. This classification is widely used by cancer registries. It is currently in its third revision (ICD-O-3). ICD-10 includes a list of ...
Waldenström macroglobulinemia (/ ˈ v æ l d ən s t r ɒ m ˌ m æ k r oʊ ˌ ɡ l ɒ b j ə l ɪ ˈ n iː m i ə / VAL-dən-strom MAK-roh-GLOB-yə-lin-EE-mee-ə, [1] [2] US also / ˈ v ɑː l d ən s t r ɛ m-/ VAHL-dən-strem - [3]) is a type of cancer affecting two types of B cells: lymphoplasmacytoid cells and plasma cells.
HeLa ( / ˈhiːlɑː /) is an immortalized cell line used in scientific research. It is the oldest human cell line and one of the most commonly used. [ 1][ 2] HeLa cells are durable and prolific, allowing for extensive applications in scientific study. [ 3][ 4] The line is derived from cervical cancer cells taken on February 8, 1951, [ 5] from ...
Oncology. Non-small-cell lung cancer ( NSCLC ), or non-small-cell lung carcinoma, is any type of epithelial lung cancer other than small-cell lung cancer (SCLC). NSCLC accounts for about 85% of all lung cancers. [ 1][ 2][ 3] As a class, NSCLCs are relatively insensitive to chemotherapy, compared to small-cell carcinoma.
HCT116 cells can also function in xenografts, with docetaxel, 5-FU, and flavopiridol limiting tumor growth in vitro. The HCT116 cell line was found to have two variations; one with a large expression of the Insp8 gene, and the other without. The Insp8 gene is part of a cell's energy metabolism process, and can affect the cellular phenotype as a ...