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Originally the cell line was named MCF-7/ADR-RES; it was renamed together with the change in classification. Two brain cancer cell lines, SNB-19 and U251, were discovered to come from the same person. This makes a mixup likely. A 61st cell line, MDA-N, has been confirmed to being derived from the misclassified MDA-MB-435 cell line.
4T1 cell culture - 50% confluence. 4T1 is a breast cancer cell line derived from the mammary gland tissue of a mouse BALB/c strain. [ 1] 4T1 cells are epithelial and are resistant to 6-thioguanine. [ 1] In preclinical research, 4T1 cells have been used to study breast cancer metastasis as they can metastasize to the lung, liver, lymph nodes ...
Characteristics. HCT116 cells have a mutation in codon 13 of the KRAS proto-oncogene, and are suitable transfection targets for gene therapy research. [ 2] The cells have an epithelial morphology and can metastasize in xenograft models. [ 1] When transducted with viral vectors carrying the p53 gene, HCT116 cells remain arrested in the G1 phase ...
MCF-7. MCF-7 is a breast cancer cell line isolated in 1970 from a 69-year-old White woman. [ 1] MCF-7 is the acronym of Michigan Cancer Foundation-7, referring to the institute in Detroit where the cell line was established in 1973 by Herbert Soule and co-workers. [ 2] The Michigan Cancer Foundation is now known as the Barbara Ann Karmanos ...
The myeloid cell line normally produces granulocytes, erythrocytes, thrombocytes, macrophages and mast cells; the lymphoid cell line produces B, T, NK and plasma cells. Lymphomas, lymphocytic leukemias, and myeloma are from the lymphoid line, while acute and chronic myelogenous leukemia, myelodysplastic syndromes and myeloproliferative diseases ...
Jurkat cells are an immortalized line of human T lymphocyte cells that are used to study acute T cell leukemia, T cell signaling, and the expression of various chemokine receptors susceptible to viral entry, particularly HIV. [ 1] Jurkat cells can produce interleukin 2, and are used in research involving the susceptibility of cancers to drugs ...
The International Classification of Diseases for Oncology (ICD-O) is a domain-specific extension of the International Statistical Classification of Diseases and Related Health Problems for tumor diseases. This classification is widely used by cancer registries. It is currently in its third revision (ICD-O-3). ICD-10 includes a list of ...
A20 cells. A20 cells, also called ATCC TIB-208, is a cell line originally derived from B-cell lymphoma in an old BALB/c mouse. [1] AT20 cells are BALB/c lymphoma cells derived from spontaneous reticulum cell neoplasm. [2] ATCC TIB-208 cells originated from B-cell lymphoma in the reticulum cell sarcoma of an elderly BALB/c mouse. [3]