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The International Classification of Diseases for Oncology (ICD-O) is a domain-specific extension of the International Statistical Classification of Diseases and Related Health Problems for tumor diseases. This classification is widely used by cancer registries. It is currently in its third revision (ICD-O-3). ICD-10 includes a list of ...
K562 cells were the first human immortalised myelogenous leukemia cell line to be established. K562 cells are of the erythroleukemia type, and the cell line is derived from a 53-year-old female chronic myelogenous leukemia patient in blast crisis. [ 1][ 2] The cells are non-adherent and rounded, are positive for the bcr:abl fusion gene, and ...
List of breast cancer cell lines. Scientists study the behaviour of isolated cells grown in the laboratory for insights into how cells function in the body in health and disease. Experiments using cell culture are used for developing new diagnostic tests and new treatments for diseases. This is a list of major breast cancer cell lines that are ...
Characteristics. HCT116 cells have a mutation in codon 13 of the KRAS proto-oncogene, and are suitable transfection targets for gene therapy research. [ 2] The cells have an epithelial morphology and can metastasize in xenograft models. [ 1] When transducted with viral vectors carrying the p53 gene, HCT116 cells remain arrested in the G1 phase ...
MCF-7. MCF-7 is a breast cancer cell line isolated in 1970 from a 69-year-old White woman. [ 1] MCF-7 is the acronym of Michigan Cancer Foundation-7, referring to the institute in Detroit where the cell line was established in 1973 by Herbert Soule and co-workers. [ 2] The Michigan Cancer Foundation is now known as the Barbara Ann Karmanos ...
TNM staging system. The TNM Classification of Malignant Tumors ( TNM) is a globally recognised standard for classifying the anatomical extent of the spread of malignant tumours (cancer). It has gained wide international acceptance for many solid tumor cancers, but is not applicable to leukaemia or tumors of the central nervous system.
A549 cells are adenocarcinomic human alveolar basal epithelial cells, and constitute a cell line that was first developed in 1972 by D. J. Giard, et al. through the removal and culturing of cancerous lung tissue in the explanted tumor of a 58-year-old caucasian male. [ 1] The cells are used as models for the study of lung cancer and the ...
4T1 cell culture - 50% confluence. 4T1 is a breast cancer cell line derived from the mammary gland tissue of a mouse BALB/c strain. [ 1] 4T1 cells are epithelial and are resistant to 6-thioguanine. [ 1] In preclinical research, 4T1 cells have been used to study breast cancer metastasis as they can metastasize to the lung, liver, lymph nodes ...